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Abeta (1-42) | Amyloid-beta peptide 1-42

291 €

AS08 329 | clonality: polyclonal | host: hen | reactivity: human

PRODUCT INFORMATION IN PDF

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6 st
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Item No:
AS08 329

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product information
Background

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067

Immunogen

synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A

Host Chicken
Clonality Polyclonal
Clone
Purity Total IgY
Format Liquid in PBS pH 8.0, 0.02% sodium azide
Quantity 100 ĩl
Reconstitution
Storage

store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.

Tested applications ELISA (ELISA), Dot Blot (Dot)
Related products

Alzheimer | available antibodies for Alzheimer's disease

Additional information
application information
Recommended dilution

1:500 (ELISA), 1:1000 (Dot)

Expected | apparent MW

4.5 kDa

Confirmed reactivity human
Predicted reactivity

bovine, chicken, dog, porcine, rabbit

Not reactive in

no confirmed exceptions from predicted reactivity known in the moment

Additional information

the antibody can detect Abeta(1-42), but does not react with Abeta(1-40), Abeta(1-41), Abeta(1-28) Abeta(1-20) or Abeta(1-17)

Selected references

to be added when available


Dot blot application example


• Membrane: Nitrocellulose
• Blocking buffer: 5% dry milk in PBS, 0.1% Tween 20
• Antibody dilution : 1:1000
• Secondary antibody: anti-chicken (HRP)
• Detection: Enhanced Chemoluminescence (pico) 30s


||| For other applications, usage on species other than stated above or any other questions, please use the LiveChat option or contact us at support@agrisera.com