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ER | Estrogen receptor

371 €

AS05 065R  |  clonality: polyclonal  |  host: rabbit  |  reactivity: human

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AS05 065R

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product information
Background

The estrogen receptor (ER) is a steroid hormone receptor. This protein functions as a nuclear receptor for estrogens such as estradiol. The two different estrogen receptor proteins produced from the ESR1 and ESR2 genes are called the alpha and beta receptors. Alternative names of the protein coded by ESR1 gene: estradiol receptor,  ER-alpha, nuclear receptor subfamily 3 group A member 1. Alternative names of the protein coded by ESR2 gene: nuclear receptor subfamily 3 group A member 2.

Immunogen

KLH conjugated synthetic peptide conserved in sequences of all known ER-alpha and ER-beta including human ER-alpha PO3372 and human ER-beta Q92731

Host Rabbit
Clonality Polyclonal
Clone
Purity Affinity purified serum
Format Lyophilized in PBS pH 7.4
Quantity 100 ĩg
Reconstitution For reconstitution add 100 ĩl of sterile water
Storage

store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Tested applications Western blot (WB)
Related products

to be added when available

Secondary antibodies

Additional information

antibody will recognize both isoforms: ER-alpha and ER-beta

application information
Recommended dilution

1: 5 000 with ECL Advance (WB)

Expected | apparent MW

60-65 kDa

Confirmed reactivity human recombinant ER
Predicted reactivity

mammals

Not reactive in

no confirmed exceptions from predicted reactivity known in the moment

Additional information

to be added when available

Selected references

to be added when available


application example: Western blot analysis

 


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