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S5a | human 26S proteasome subunit

323 €

AS01 019  |  clonality: polyclonal  |  host: rabbit  |  reactivity: human

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AS01 019

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Background

Proteasome-dependent degradation serves an essential role in the removal of a wide variety of key nuclear and cytosolic proteins. Substrates are targeted for proteolysis by the ubiquitin pathway before being degraded by the 26 S proteasome. The subunit of the proteasome, S5a, was identified to bind to polyubiquitin in vitro and thus proposed to act as a substrate recognition component. Alternative names: 26S proteasome non-ATPase regulatory subunit 4, Rpn10, multiubiquitin chain-binding protein, antisecretory factor 1, ASF, AF

Immunogen

Recombinant human S5a Proteasome subunit also known as Rpn10 P55036

Host Rabbit
Clonality Polyclonal
Clone
Purity Serum
Format Lyophilized
Quantity 100 ĩl
Reconstitution For reconstitution add 100 ĩl of sterile water.
Storage

store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Tested applications western blot (WB)
Related products

AS01 012 | anti-DS5a | Drosophila 26S proteasome subunit Rpn10

Secondary antibodies

Additional information
application information
Recommended dilution

1:2000 (WB)

Expected | apparent MW

40 kDa

Confirmed reactivity human
Predicted reactivity
Not reactive in

Drosophila melanogaster

Additional information
Selected references Lundgren et al. (2003). Use of RNA interference and complementation to study the function of the Drosophila and human 26S proteasome subunit S13. Mol Cel Biol 23:5320-5330.


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