|
product information
|
| background |
|
Factor VII is a 52 kDa multi-domain, single chain plasma glycoprotein synthesised in the liver and having abnormal circulating concentration of between 400 and 600 g/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, Factor Xa, Factor IXa or Factor XIIa. Factor VIIa converts Factor X to Factor Xa, which in turn converts prothrombin to thrombin. |
| immunogen |
|
Purified full length recombinant protein P08709 |
| antibody format |
|
hen; |
polyclonal; |
|
total IgY at 11 mg/ml in 0.9% NaCl, 0.1% sodium azide |
liquid |
|
| quantity |
|
|
| storage |
|
store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes. |
| tested applications |
|
Western blot (WB) |
| related products |
|
AS00 001 | anti-Coagulation factor VIIa
IMS01-015-308 | anti-Coagulation factor VIII
AS05 058 | anti-Coagulation factor IX IMS01-137-306 | anti-Coagulation factor XII
|
| additional information |
|
he IgY fraction is isolated by a two-step PEG precipitation procedure followed by ammonium sulphate precipitation |
application information
|
| recommended dilution |
|
1: 5 000 - 1: 10 000 with standard ECL (WB), 1: 1000 - 1: 5 000 (ELISA) |
| expected | apparent MW |
|
52 kDa |
| confirmed reactivity |
|
human |
| predicted reactivity |
|
primates |
| not reactive in |
|
no confirmed exceptions from predicted reactivity known in the moment |
| additional information |
|
the antibody, in dilution 1: 10 000, will detect 1 ng of factor VII in immunoblotting |
| selected references |
|
to be added when available |
||| For applications or usage on species others than stated above Agrisera offers a payment-after-testing option. To learn more about this or for any questions on this product, please use LiveChat option in the left menu or contact us at support@agrisera.com
 Save as PDF
|
