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product information
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| background |
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Human Kallikrein 5 (KLK5) is a serine protease produced in its inactive form. It is found in catalytically active form in stratum corneum. It has been reported to degrade desmosomes/corneodesmosomes, suggesting that it is involved in desquamtion. Egelrud et al. (2005) hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. J Invest Dermatol, 124(1):198-203.Alternative names: stratum corneum tryptic enzyme, Kallikrein-like protein 2, KLK-L2 |
| immunogen |
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KLH-conjugated mix of two synthetic peptides: one chosen from C-terminal and the other one from midregion of human KLK5 Q9Y337 |
| antibody format |
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rabbit; |
polyclonal; |
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serum; |
lyophilized |
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| quantity |
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200 µl |
- for reconstitution add 200 µl of sterile water |
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| storage |
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store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes. |
| tested applications |
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Western blot (WB) |
| related products |
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AS06 101 | anti-Kallikrein 14 AS06 103 | anti-pro-Kallikrein 5 |
| additional information |
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to be added when available |
application information
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| recommended dilution |
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1: 1000 with standard ECL (WB) |
| expected | apparent MW |
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32 | 37 kDa |
| confirmed reactivity |
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human |
| predicted reactivity |
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human |
| not reactive in |
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no confirmed exceptions from predicted reactivity known in the moment |
| additional information |
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antibody is recognizing denatured active Kallikrein 5 |
| selected references |
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to be added when available |
Western blot experiment example 
||| For applications or usage on species others than stated as confirmed above Agrisera offers a payment-after-testing option. To learn more about this or for any questions on this product, please use the LiveChat option in the left menue bar or contact us at support@agrisera.com
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