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KLK5 | Kallikrein 5

345 €

AS06 102  |  clonality: polyclonal  |  host: rabbit  |  reactivity: human

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Item No:
AS06 102

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product information
Background

Human Kallikrein 5 (KLK5) is a serine protease produced in its inactive form. It is found in catalytically active form in stratum corneum. It has been reported to degrade desmosomes/corneodesmosomes, suggesting that it is involved in desquamtion. Egelrud et al. (2005) hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. J Invest Dermatol, 124(1):198-203.Alternative names: stratum corneum tryptic enzyme,  Kallikrein-like protein 2, KLK-L2

Immunogen

KLH-conjugated mix of two synthetic peptides: one chosen from C-terminal and the other one from midregion of human KLK5 Q9Y337

Host Rabbit
Clonality Polyclonal
Clone
Purity Serum
Format Lyophilized
Quantity 200 ĩl
Reconstitution For reconstitution add 200 ĩl of sterile water
Storage

store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Tested applications Western blot (WB)
Related products

AS06 101 | anti-Kallikrein 14

AS06 103 | anti-pro-Kallikrein 5

Secondary antibodies

Additional information
application information
Recommended dilution

1: 1000 with standard ECL (WB)

Expected | apparent MW

32 | 37 kDa

Confirmed reactivity human
Predicted reactivity

human

Not reactive in

no confirmed exceptions from predicted reactivity known in the moment

Additional information

antibody is recognizing denatured active Kallikrein 5

Selected references

to be added when available


Western blot experiment example

 


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