8-Hydroxyguanosine | DNA/RNA oxidative damage
AS10 708-100 | clonality: monoclonal | host: mouse | reactivity: hydroxy guanosine
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needs to be determined for each application
|Expected | apparent MW|
|Confirmed reactivity||Recognizes markers of oxidative damage to DNA (8-hydroxy-2’-deoxyguanosine, 8-hydroxyguanine and 8-hydroxyguanosine)|
|Not reactive in||
no confirmed exceptions from predicted reactivity known in the moment
protocol for immunostaining using this antibody can be found here
|Selected references||Haigh and Drew (2015). Cavitation during the protein misfolding cyclic amplification (PMCA) method - The trigger for de novo prion generation? Biochem Biophys Res Commun. 2015 Apr 17. pii: S0006-291X(15)00726-3. doi: 10.1016/j.bbrc.2015.04.048.
Poborilova et al. (2015). DNA hypomethylation concomitant with the overproduction of ROS induced by naphthoquinone juglone on tobacco BY-2 suspension cells. Environmental and Experimental Botany, Volume 113, May 2015, Pages 28–39.
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