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A1AGP | Alpha-1-acid glycoprotein

323 €

AS01 015  |  clonality: polyclonal  | host: rabbit  |  reactivity: rat

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Item No:
AS01 015

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product information
Background

Alpha-1-acid glycoprotein (A1AGP) or Orosomucoid (OMD) is a plasma glycoprotein synthesized by the liver. The protein is believed to regulate the interaction between blood cells and endothelial cells, and therefore also regulates the extravasation of the cells during infection and inflammation. A1AGP is a major acute phase reactant, both in man and in rat. It's concentration in blood plasma is elevated during acute inflammation, such as rheumatoid arthritis, bacterial infections, etc, and can be used for the diagnosis of inflammatory conditions.

Immunogen

rat alpha-1-acid glycoprotein (A1AGP) or orosomucoid (OMD) UniProt: P02764

Host Rabbit
Clonality Polyclonal
Clone
Purity Serum
Format Lyophilized
Quantity 200 ĩl
Reconstitution For reconstitution add 200 ĩl of sterile water
Storage

store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Tested applications Western blot (WB), ELISA (ELISA), immunoprecipitation (IP), radioimmunoassay (RIA)
Related products

secondary antibodies

Additional information
application information
Recommended dilution

1: 2000 (WB);  use at an assay dependent dilution in (ELISA), (IP), (RIA)

Expected | apparent MW

44 kDa

Confirmed reactivity

rat

Predicted reactivity

rat

Not reactive in

no confirmed exceptions from predicted reactivity known in the moment

Additional information
Selected references

Olofsson et al. (2002) Positional identification of Ncf1 as a gene that regulates arthritis severity in rats. Nat Genet, 33, 25-32.

Olofsson et al. (2003) Identification and isolaton of dominant sesceptibility loci for pristane-induced arthritis. J Immunol, 171, 407-16.



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