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TH | Tyrosine Hydroxylase

350 €

AS13 2696 | clonality: polyclonal | host: rabbit | reactivity: rat, mouse and guinea pig

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AS13 2696

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Background

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. It plays an important role in the physiology of adrenergic neurons.

Immunogen

A synthetic peptide as part of human Tyrosine Hydroxylase conjugated to KLH. The peptide is homologous with the corresponding sequence derived from TH protein in rat.

Host Rabbit
Clonality Polyclonal
Clone
Purity Serum
Format Lyophilized
Quantity 100 ĩl
Reconstitution For reconstitution please add 100 ĩl of sterile water
Storage

After reconstitution keep aliquots at -20ºC for a higher stability, and at  4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Tested applications Immunohistochemistry (IHC)
Related products
Additional information
application information
Recommended dilution

A dilution of 1:2000 to 1: 5000 is recommended for this application. This is a superb antibody for detection of tyrosine hydroxylase containing neurons exhibiting an intense labelling with a negligible background. This antiserum has proven extremely useful for staining of catecholaminergic neurons. It stains nicely and intensely dendritic processes and fine nerve terminals. We recommend mouse or rat brain containing catecholaminergic neurons as a positive control for this antibody, for example brain stem or striatum. Optimal dilutions/concentrations should be determined by the end user.

Expected | apparent MW
Confirmed reactivity

rat, mouse and guinea pig

Predicted reactivity

not yet tested in other species

Not reactive in
Additional information

to be added when available

Selected references

to be added when available


Application example



Immunohistochemical staining of catecholaminergic neurons in the rat brain stem.








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