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Animal cell antibodies / Neurosteroids/Neurobiology |
THDOC | tetrahydrodeoxycorticosterone
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product information
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| background |
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TetraHydroDesOxyCorticosterone (THDOC) is a stress related neuroactive steroid. THDOC is a metabolite of desoxycoritcosterone (DOC) and progesterone and DOC is a steroid in the synthesis pathway to aldosterone. THDOC is produced by the adrenal in parallel with cortisol at stress and is regulated by ACTH. THDOC is a potent positive modulator of the GABA A receptor. THDOC passes the blood-brain barrier and can be found in the brain after stress in nanomolar concentrations. |
| immunogen |
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BSA-coupled THDOC |
| antibody format |
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hen; |
polyclonal; |
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total IgY in PBS pH 8.0 + 0.02% sodium azide; |
liquid |
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| quantity |
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| storage |
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store at 4°C or at -20°C for long-term storage; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes. |
| tested applications |
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radioimmunoassay (RIA) |
| related products |
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to be added when available |
| additional information |
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to be added when available |
application information
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| recommended dilution |
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1: 1000 (RIA) |
| expected | apparent MW |
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not applicable |
| confirmed reactivity |
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THDOC |
| predicted reactivity |
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not applicable |
| not reactive in |
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no confirmed exceptions from predicted reactivity known in the moment |
| additional information |
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method description available under "more information" |
| selected references |
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to be added when available |
||| For applications or usage on species others than stated above Agrisera offers a payment-after-testing option. To learn more about this or for any questions on this product, please use LiveChat option in the left menu or contact us at support@agrisera.com
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