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FGF2 | Basic fibroblast growth factor

304 €

IMS01-138-313  |  clonality: polyclonal  |  host: hen  |  reactivity: human 

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Item No:
IMS01-138-313

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product information
Background

Basic Fibroblast Growth Factor (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth.  FGF2  mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Immunogen

purified full length native protein P09038

Host Hen
Clonality Polyclonal
Clone
Purity Total IgY fraction
Format Liquid in 0.9 % NaCl, 0.1 % sodium azide
Quantity 100 ĩl (13 mg/ml)
Reconstitution
Storage

store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.

Tested applications Western blot (WB)
Related products
Additional information

the IgY fraction is isolated by a two-step PEG precipitation procedure followed by ammonium sulphate precipitation

application information
Recommended dilution

1: 1000 with standard ECL (WB), 1: 1000 (ELISA)

Expected | apparent MW

18 kDa

Confirmed reactivity

human

Predicted reactivity

bovine, chicken, mouse, rat, sheep

Not reactive in

no confirmed exceptions from predicted reactivity known in the moment

Additional information

reacts with  human recombinant FGF2. No reactivity with other human serum proteins

Selected references

to be added when available



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