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IL2 | Interleukin-2

304 €

IMS01-127-320  |  clonality: polyclonal  |  host: hen  |  reactivity: human

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IMS01-127-320

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product information
Background

Human interleukin-2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin-4 (IL4) and interleukin-7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies.

Immunogen

purified full length recombinant protein P60568

Host Chicken
Clonality Polyclonal
Clone
Purity Total IgY fraction
Format Liquid in 0.9% NaCl, 0.1% sodium azide
Quantity 100 ĩl (9.2 mg/ml)
Reconstitution
Storage Store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Tested applications Total, purified IgY
Related products

IMS01-145-319 | anti-Interferon gamma

Secondary antibodies

Additional information The IgY fraction is isolated by a two-step PEG precipitation. procedure followed by ammonium sulphate precipitation.
application information
Recommended dilution 1 : 1000-1 : 5 000 (ELISA), 1 : 1000-1 : 5 000 (WB)
Expected | apparent MW

17kDa

Confirmed reactivity Human
Predicted reactivity Primates
Not reactive in No confirmed exceptions from predicted reactivity are currently known.
Additional information The antibody, in dilution 1: 1000, will detect 10 ng of interleukin-2 in immunoblotting.
Selected references

to be added when available



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