STX | saxitoxin, Serum (0.1ml)

345 €

AS11 1663 | clonality: polyclonal | host: rabbit | reactivity: saxitoxin

product information

background

Saxitoxin (STX) is a neurotoxin that acts as a selective sodium channel blocker and is naturally produced by certain species of marine dinoflagellates (Alexandrium sp., Gymnodinium sp., Pyrodinium sp.) and cyanobacteria (Anabaena sp., some Aphanizomenon spp., Cylindrospermopsis sp., Lyngbya sp., Planktothrix sp.). Ingestion of STX (usually through shellfish contaminated by toxic algal blooms) is responsible for the human illness known as paralytic shellfish poisoning (PSP). Saxitoxin, one of the most potent natural toxins known, acts on the voltage-gated sodium channels of nerve cells, preventing normal cellular function and leading to paralysis.

immunogen

BSA-conjugated saxitoxin

antibody format

rabbit

polyclonal

serum

liquid

quantity

0.1 ml

storage

4°C up to one month or in aliquots at -20°C for long time storage. Avoid repeated freezing and thawing.

tested applications

ELISA

related products

AS11 1696 | anti-saxitoxin, antibodies in serum format, larger pack size - 1 ml

additional information

Antibodies are present in phosphate buffered saline, pH 7.2, 0.05% sodium azide as preservative.

application information
recommended dilution		To be determined by end user.
expected \| apparent MW		n.a.
confirmed reactivity		toxin from marine dinoflagellates, cyanobacteria and mussels
predicted reactivity		n.a.
not reactive in		no confirmed exceptions from predicted reactivity known in the moment
additional information		The term saxitoxin can also refer to the entire suite of related neurotoxins produced by these microorganisms, which include pure STX, neosaxitoxin (neoSTX), the gonyautoxins (GTX) and decarbamoylsaxitoxin (dcSTX).
selected references		to be added when available

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