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TF | Transferrin

304 €

IMS02-020-322  |  clonality: polyclonal  |  host: hen  |  reactivity: human

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IMS02-020-322

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product information
Background

Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains, each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.

Immunogen

purified full length native protein P02787

Host Hen
Clonality Polyclonal
Clone
Purity Affinity purified IgY
Format Liquid in 0.15M sodium chloride, 0.02M sodium phosphate, 0.1% sodium azide, pH 7.2
Quantity 100 ĩl (1 ĩg/ĩl)
Reconstitution
Storage

store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.

Tested applications Western blot (WB)
Related products

IMS06-020-323 | TF | transferrin, hen antibody labelled with biotin

AS10 1370 | anti-TF | transferrin, goat antibody

Secondary antibodies

Additional information

affinity purified IgY on human tranferrin agarose

application information
Recommended dilution

1: 1000 with standard ECL (WB)

Expected | apparent MW

77 kDa

Confirmed reactivity

human

Predicted reactivity

primates

Not reactive in

no confirmed exceptions from predicted reactivity known in the moment

Additional information

only one precipitin arc in immunodiffusion against normal human serum, dilution 1: 10, or human transferrin. Only one precipitin arc in immunoelectrophoresis against normal human serum, or human transferrin.

Selected references

to be added when available



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