TF | transferrin (goat antibody)
AS10 1370 | Clonality: Polyclonal | Host: Goat | Reactivity:Human transferrin
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Product Information
Immunogen
Human transferrin AAB22049
Host
Goat
Clonality
Polyclonal
Purity
Immunogen Affinity purified using solid phase human Transferrin.
Format
Liquid
Quantity
1 mg
Storage
Store at 2-8°C.
Tested applications
Immunoassays
Recommended dilution
The optimal working dilution should be determined by the investigator
Expected | apparent MW
77 kDa
Reactivity
Confirmed reactivity
Human transferrin
Predicted reactivity
Primates
Not reactive in
No confirmed exceptions from predicted reactivity are currently known
Application examples
Additional information
Affinity purified using solid phase human Transferrin. Antibody concentration is > 4.5 mg/ml (E 1% at 280 nm = 13.0).
Antibody is supplied in 10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2. Contains 0.05% (w/v) sodium azide as preservative. Antibody purity is > 95% based on SDS-PAGE.
Background
Background
Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains, each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.
Product citations
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