TF | transferrin (goat antibody)

AS10 1370 | Clonality: Polyclonal | Host: Goat | Reactivity:Human transferrin


product information
Background		Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains, each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.
Immunogen		human transferrin AAB22049
Host		Goat
Clonality		Polyclonal
Clone
Purity		Affinity purified
Format		Liquid
Quantity		1 mg
Reconstitution
Storage		Store at 2-8°C.
Tested applications		Immunoassays
Related products		IMS02-020-322 \| TF \| Transferrin, hen antibody IMS06-020-323 \| TF \| Transferrin labelled with biotin, hen antibody anti-goat secondary antibodies
Additional information

application information
Recommended dilution		The optimal working dilution should be determined by the investigator.
Expected \| apparent MW		77 kDa
Confirmed reactivity		Human transferrin
Predicted reactivity		Primates
Not reactive in		No confirmed exceptions from predicted reactivity are currently known.
Additional information		Affinity purified using solid phase human Transferrin. Antibody concentration is > 4.5 mg/ml (E 1% at 280 nm = 13.0). Antibody is supplied in 10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2. Contains 0.05% (w/v) sodium azide as preservative. Antibody purity is > 95% based on SDS-PAGE.
Selected references		to be added when available

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