A1M | Human alpha-1-microglobulin

AS13 2670 | Clonality: Polyclonal |  Host: Hen | Reactivity: Human

A1M | Human alpha-1-microglobulin  in the group Human/Animal Antibodies / Human Proteins / Other Human proteins at Agrisera AB (Antibodies for research) (AS13 2670)


348 €

Info: Add review
product information

Alpha-1-microglobulin is a 27-kDa glycoprotein with immunosuppressive properties. A gene AMBP in the lipocalin cluster encodes alpha-1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha-1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins are secreted to the blood separately. Alpha-1-microglobulin is found in blood and in connective tissue in most organs. It is most abundant at interfaces between the cells of the body and the environment, such as in lungs, intestine, kidneys and placenta. Alpha 1-microglobulin is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.

Immunogen Full-length human alpha-1-microglobulin (A1M), purified from human urine.
Host Chicken
Clonality Polyclonal
Purity Total IgY
Format Liquid in PBS
Quantity 100 ĩg
Storage Store lyophilized/reconstituted at -20°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Tested applications ELISA (ELISA), Radioimmunoassay (RIA), Western blot (WB)
Related products

AS01 014 | AMBP | Alpha-1-microglobulin

Secondary antibodies

Additional information

IgY concentration is 19,8 mg/ml

application information
Recommended dilution 1 : 5000 (ELISA), 1 : 2000 (WB)
Expected | apparent MW

27 kDa

Confirmed reactivity Human
Predicted reactivity Human, Rabbit, Cat, Rat, Macaca fascicularis, Pan troglodytes, Gorilla, Ailuropoda melanoleuca
Not reactive in No confirmed exceptions from predicted reactivity are currently known.
Additional information
Selected references Rutardottir et al. (2016). The cysteine 34 residue of A1M/α1-microglobulin is essential for protection of irradiated cell cultures and reduction of carbonyl groups. Free Radic Res. 2013 Jul;47(6-7):541-50. doi: 10.3109/10715762.2013.801555. Epub 2013 May 29.
Olsson MG et al. (2013). The radical-binding lipocalin A1M binds to a Complex I subunit and protects mitochondrial structure and function. Antioxid Redox Signal. 2013 Jun 1;18(16):2017-28.

||| For other applications, usage on species other than stated above or any other questions, please use the LiveChat option or contact us at