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Tag Antibody Set 

FVIIa | Coagulation factor VIIa (500 ĩg)

AS00 001-500  |  Clonality: Polyclonal  |  Host: Rabbit  |  Reactivity: Human 

FVIIa | Coagulation factor VIIa (500 ĩg) in the group Antibodies for Human/Animal  / Human Proteins / Immunology at Agrisera AB (Antibodies for research) (AS00 001-500)

PRODUCT INFORMATION IN PDF

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1645 €

Datasheet Product citations Add review

Product Information

Immunogen

Recombinant human Factor VIIa (NovoSeven ®, Novo Nordisk  A/S Denmark)

Host Rabbit
Clonality Polyclonal
Purity Affinity purified IgG in PBS, pH 7.4
Format Lyophilized
Quantity

500 ug

Reconstitution For reconstitution add 500 µl of sterile water.
Storage Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them, to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Tested applications Prothrombin assay with human plasma (PT), thrombin generation assay, inhibition assay with Factor VIIa with TF and a chromogenic substrate, inDirect ELISA (I-ELISA)
Recommended dilution 1 : 15 000 (I-ELISA)
Expected | apparent MW

52 kDa

Reactivity

Confirmed reactivity Human
Predicted reactivity Primates
Not reactive in No confirmed exceptions from predicted reactivity are currently known.

Application examples

Additional information

Additional information No significant difference in binding to Factor VII and Factor VIIa.

Antibody is purified to total IgG fraction, followed by purification on specific FVIIa column.

Related products

Related products

AS00 001 | Anti-FVIIa | Coagulation factor VIIa (50 µg), rabbit antibodies

IMS01-015-308 | Anti-F8 | Coagulation factor VIII, chicken antibodies

IMS01-118-307 | Anti-F7 | Coagulation factor VII, chicken antibodies

IMS01-137-306 | Anti-F12 | Coagulation factor XII, chicken antibodies

Background

Background

Factor VIIa (FVIIa) is a key serine protease involved in the initiation of the coagulation cascade. FVIIa requires tissue factor (TF), a membrane bound protein, as an essential cofactor for maximal activity towards its biological substrates Factor X, Factor IX and Factor VII (FVII).

Product citations

Selected references Lopez-Vilchez et al. (2009). Traffic of rFVIIa through Endothelial Cells and Redistribution into Subendothelium: Implications for a Prolonged Hemostatic Effect. Journal of Coagulation Disorders, October 1: (1). (immunolocalization)

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