TrkB | Tyrosine Kinase Receptor B

AS13 2697 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Rat, Mouse

TrkB | Tyrosine Kinase Receptor B in the group Human/Animal Antibodies / Neurosteroids/Neurobiology at Agrisera AB (Antibodies for research) (AS13 2697)


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product information

TrkB is a member of the neurotrophic tyrosine receptor kinase family. It is a membrane-bound receptor and upon neurotrophin binding, it phosphorylates itself as well as MAPK pathways members. TrkB is the receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). It is Involved in the development and/or maintenance of the nervous system. 


Extracellular domain of glycosylated mouse TrkB protein produced in CHO cells was used as the immunogen. As shown for similar antisera, it is anticipated that this antibody will block the TrkB receptor binding of corresponding neurotrophin ligand.

Host Rabbit
Clonality Polyclonal
Purity Serum
Format Lyophilized
Quantity 100 ĩl
Reconstitution For reconstitution add 100 ĩl of sterile water.

After reconstitution keep aliquots at -20ºC for a higher stability, and at  4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Tested applications ELISA (ELISA), Immunohistochemistry (IHC)
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Additional information
application information
Recommended dilution 1 : 10 000 (1-site ELISA), 1 : 1000-1 : 3000 (IHC). Optimal dilutions/concentrations should be determined by the end user.
Expected | apparent MW
Confirmed reactivity Rat, Mouse
Predicted reactivity
Not reactive in
Additional information
Selected references

to be added when available

Application example

Immunohistochemical staining of Tyrosine Kinase Receptor B (TrkB) in rat ventral horn (free floating cryostat section) using rabbit antibody (AS13 2697) at a dilution of 1 in 3000. Courtesy of Professor Xin Fu Zhou, The Flinders University of South Australia

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