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Cadherin-6 (clone 2B6)

AS16 4005 | Clonality: Monoclonal | Host: Mouse | Reactivity: Human, Rat

Cadherin-6 (clone 2B6) in the group Antibodies for Human/Animal  / Human Proteins / Developmental biology at Agrisera AB (Antibodies for research) (AS16 4005)

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Product Information

Immunogen Baculovirus infected Sf9 cells. UniProt: P55285
Host Mouse
Clonality Monoclonal
Subclass/isotype IgG1
Purity Protein A/G purified
Format Liquid
Quantity 100 µg
Storage Store at -20°C.
Tested applications Immunocytochemistry (ICC) (ICH), Immunohistochemistry (IHC), Western blot (WB)

Reactivity

Confirmed reactivity Human, Rat
Not reactive in No confirmed exceptions from predicted reactivity are currently known.

Application examples

Additional information

Additional information Provided in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT. 

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Specific Activity: 170 U/mg. One unit is defined as the amount of enzyme that will transfer 1 nmol phosphate to the tyrosine substrate per minute at pH 7.4 and 30¼C.
Assay buffer: 50 mM HEPES, pH 7.4, 3 mM MgCl2, 3 mM MnCl2, 1 mM DTT, 3 uM Na-orthovanadate, 0.1 mM ATP, 30 ug/ml Poly (Glu:Tyr)4:1 substrate, and 2 ug /ml recombinant Flt1.

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Background

Background Cadherins is a group of transmembrane glycoproteins which are Ca2+-dependent and cell adhesion proteins. They are expressed in different ways in various tissues. The maintenance of tissue integrity and morphogenesis is their function. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney. Many renal cell carcinomas are derived from there.

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