IKP

Capsaicin receptor

Product no: AS13 2701

AS13 2701 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human, Mouse, Rat

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  • Product Info
  • Immunogen: A synthetic peptide of human capsaicin receptor protein conjugated to KLH has been used as the immunogen,
    Host: Rabbit
    Clonality: Polyclonal
    Purity: Serum
    Format: Lyophilized
    Quantity: 100 l
    Reconstitution: For reconstitution add 100 l of sterile water
    Storage: After reconstitution keep aliquots at -20C for a higher stability. and at 4C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
    Tested applications: Immunohistochemistry (IHC)
    Recommended dilution: 1 : 1000-1 : 2000 (IHC)
  • Reactivity
  • Confirmed reactivity: Human, Mouse, Rat
  • Application Examples
  • Application example





    Immunohistochemical staining of rat spinal cord using rabbit antibody to human capsaicin receptor, catalog number AS13 2701.


    immunofluorescence of neurofilaments with capsaicin antibodies

    Immunohistochemistry showing capsaicin receptor (TRPV1, red) and neurofilament-heavy chain (NFL, green) reactivity in nociceptive sensory neurons derived from hESC. Fixation: 4% PFA 10 min. on ice. Blocking: 10% FCS/PBST for 1h at RT Primary: 1:100 in blocking solution for 1h at RT Secondary: 1:500 in blocking solution for 1h at RT, secondary antibodies: donkey anti-mouse 488 and donkey anti-rabbit 568.

    Courtesy of Dr. Iwan Jones, Umeå University, Sweden
  • Background
  • Background:

    Capsaicin receptor is predominantly expressed in trigeminal and dorsal root sensory ganglia. Isoform 1 and isoform 3 are also expressed in brain and peripheral blood mononuclear cells. Synonyms: The transient receptor potential cation channel subfamily V member 1 (TrpV1) and the vanilloid receptor 1

  • Product Citations
  • Selected references: Jones et al. (2018). Development and validation of an in vitro model system to study peripheral sensory neuron development and injury. Sci Rep. 2018 Oct 29;8(1):15961. doi: 10.1038/s41598-018-34280-3.
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