AS13 2701 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human, Mouse, Rat
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A synthetic peptide of human capsaicin receptor protein conjugated to KLH has been used as the immunogen.
After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Immunohistochemical staining of rat spinal cord using rabbit antibody to human capsaicin receptor, catalog number AS13 2701.
Immunohistochemistry showing capsaicin receptor (TRPV1, red) and neurofilament-heavy chain (NFL, green) reactivity in nociceptive sensory neurons derived from hESC. Fixation: 4% PFA 10 min. on ice. Blocking: 10% FCS/PBST for 1h at RT Primary: 1:100 in blocking solution for 1h at RT Secondary: 1:500 in blocking solution for 1h at RT, secondary antibodies: donkey anti-mouse 488 and donkey anti-rabbit 568.
Courtesy of Dr. Iwan Jones, Umeå University, Sweden
Capsaicin receptor is predominantly expressed in trigeminal and dorsal root sensory ganglia. Isoform 1 and isoform 3 are also expressed in brain and peripheral blood mononuclear cells. Synonyms: The transient receptor potential cation channel subfamily V member 1 (TrpV1) and the vanilloid receptor 1