Capsaicin receptor
AS13 2701 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human, Mouse, Rat

Data sheet | Product citations | Add review |
Product Information
Immunogen
A synthetic peptide of human capsaicin receptor protein conjugated to KLH has been used as the immunogen,
Host
Rabbit
Clonality
Polyclonal
Purity
Serum
Format
Lyophilized
Quantity
100 ĩl
Reconstitution
For reconstitution add 100 ĩl of sterile water
Storage
After reconstitution keep aliquots at -20šC for a higher stability. and at 4šC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Tested applications
Immunohistochemistry (IHC)
Recommended dilution
1 : 1000-1 : 2000 (IHC)
Reactivity
Confirmed reactivity
Human, Mouse, Rat
Application examples
Application examples
Application example

Immunohistochemical staining of rat spinal cord using rabbit antibody to human capsaicin receptor, catalog number AS13 2701.
Immunohistochemistry showing capsaicin receptor (TRPV1, red) and neurofilament-heavy chain (NFL, green) reactivity in nociceptive sensory neurons derived from hESC. Fixation: 4% PFA 10 min. on ice. Blocking: 10% FCS/PBST for 1h at RT Primary: 1:100 in blocking solution for 1h at RT Secondary: 1:500 in blocking solution for 1h at RT, secondary antibodies: donkey anti-mouse 488 and donkey anti-rabbit 568.
Courtesy of Dr. Iwan Jones, Umeå University, Sweden

Immunohistochemical staining of rat spinal cord using rabbit antibody to human capsaicin receptor, catalog number AS13 2701.

Immunohistochemistry showing capsaicin receptor (TRPV1, red) and neurofilament-heavy chain (NFL, green) reactivity in nociceptive sensory neurons derived from hESC. Fixation: 4% PFA 10 min. on ice. Blocking: 10% FCS/PBST for 1h at RT Primary: 1:100 in blocking solution for 1h at RT Secondary: 1:500 in blocking solution for 1h at RT, secondary antibodies: donkey anti-mouse 488 and donkey anti-rabbit 568.
Courtesy of Dr. Iwan Jones, Umeå University, Sweden
Additional information
Background
Background
Capsaicin receptor is predominantly expressed in trigeminal and dorsal root sensory ganglia. Isoform 1 and isoform 3 are also expressed in brain and peripheral blood mononuclear cells. Synonyms: The transient receptor potential cation channel subfamily V member 1 (TrpV1) and the vanilloid receptor 1
Product citations
Selected references
Jones et al. (2018). Development and validation of an in vitro model system to study peripheral sensory neuron development and injury. Sci Rep. 2018 Oct 29;8(1):15961. doi: 10.1038/s41598-018-34280-3.
Related products: Capsaicin receptor
AS12 1962 | Clonality: Polyclonal | Host: Donkey | Reactivity: Rabbit...
206 €
AS09 634 | Clonality: Polyclonal | Host: Goat | Reactivity: Rabbit IgG (H&L)
165 €
AS16 3516 | Clonality: Polyclonal | Host: Goat | Reactivity: Rabbit IgG
179 €
AS15 2839 | Clonality: Polyclonal | Host: Llama | Reactivity: Rabbit IgG (H...
185 €