CASP3 | Caspase-3 (clone AM 1 4)
AS16 4001 | Clonality: Monoclonal | Host: Mouse | Reactivity: Human
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Product Information
Immunogen
Recombinant human Caspase-3 protein. UniProt: P42574
Host
Mouse
Clonality
Monoclonal
Subclass/isotype
IgG
Purity
Protein A/G purified
Format
Liquid
Quantity
100 µg
Storage
Store at -20°C.
Tested applications
Western blot (WB)
Recommended dilution
The optimal working dilution should be determined by the investigator.
Reactivity
Confirmed reactivity
Human
Not reactive in
No confirmed exceptions from predicted reactivity are currently known.
Application examples
Additional information
Additional information
Provided in phosphate buffered saline, contains 0.08% sodium azide.
Background
Background
Caspase-3 is involved in the activation cascade of caspases, this cascade is responsible for apoptosis execution. It cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Caspase-3 belongs to the group of effector caspases that are involved in the cleavage of multiple substrates including the cytokeratins, PARP, alpha fodrin, NuMA and others.
Product citations
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