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CFH | Complement factor H

IMS01-066-309  |  Clonality: Polyclonal  |  Host: Hen |  Reactivity: Human

CFH | Complement factor H in the group Antibodies for Human/Animal  / Human Proteins / Immunology at Agrisera AB (Antibodies for research) (IMS01-066-309)

DATA SHEET IN PDF

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336
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Product name, number (Agrisera, Sweden)

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Product Information

Immunogen

purified full length native protein P08603

Host Chicken
Clonality Polyclonal
Purity Total IgY fraction
Format Liquid in 0.9% NaCl, 0.1% sodium azide
Quantity 100 µl (25.2 mg/ml)
Storage Store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Tested applications Total, purified IgY
Recommended dilution 1 : 32 (ID)
Expected | apparent MW

140 kDa

Reactivity

Confirmed reactivity Human
Predicted reactivity Human
Not reactive in No confirmed exceptions from predicted reactivity are currently known.

Application examples

Additional information

Additional information The IgY fraction is isolated by a two-step PEG precipitation. procedure followed by ammonium sulphate precipitation.

Only one precipitin arc in immunodiffusion against normal human serum, dilution 1:10, or human factor H (β1H). Only one precipitin arc in immunoelectrophoresis against normal human serum or human factor H (β1H).

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Secondary antibodies

Background

Background

The Complement factor H protein is secreted into the bloodstream and acts in the regulation of complement activation. Mutations leading to changes in this protein have been linked with HUS (hemolytic-uremic syndrome) and chronic hypocomplementemic nephropathy.

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