CHGA | Chromogranin A
IMS01-126-301 | Clonality: Polyclonal | Host: Hen | Reactivity: Human
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purified full length native protein UniProt: P10645
IgY fraction at 12.2 mg/ml. IgY fraction was isolated by a two-step PEG precipitation procedure followed by ammonium sulphate precipitation
Chromogranin A (a protein of 457 amino acids which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.