Anti-Complement component C4 (human) antibodies

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  CO4 | Complement component C4
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      <p><strong>IMS02-032-303</strong>  |  Clonality: <strong>Polyclonal</strong>  |  Host:<strong> Hen</strong>  |  Reactivity:<strong> Human</strong></p>  
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      <h3>Product Information</h3>
          
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          <span>Immunogen</span>
          <span><p>full length native protein <a href="http://www.uniprot.org/uniprot/P0C0L4" target="_blank">P0C0L4</a> purified from human plasma</p></span>
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          <span>Host</span>
          <span>Chicken</span>
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          <span>Clonality</span>
          <span>Polyclonal</span>
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          <span>Purity</span>
          <span>Affinity purified IgY</span>
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          <span>Format</span>
          <span>Liquid in 0.15M sodium chloride, 0.02M sodium phosphate, 0.1% sodium azide, pH 7.2</span>
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          <span>Quantity</span>
          <span>100 µl (1 mg/ml)</span>
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          <span>Storage</span>
          <span>Store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.</span>
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          <span>Tested applications</span>
          <span>Affinity purified IgY</span>
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          <span>Recommended dilution</span>
          <span>1 : 2000 (ELISA), 1 : 1000 (WB)</span>
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          <span>Expected | apparent MW</span>
          <span><p>193 kDa</p></span>
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      <h3>Reactivity</h3>
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          <span>Confirmed reactivity</span>
          <span>Human</span>
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          <span>Predicted reactivity</span>
          <span>Human</span>
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          <span>Not reactive in</span>
          <span>No confirmed exceptions from predicted reactivity are currently known.</span>
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       <h3>Additional information</h3>
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          <span>Additional information</span>
          <span>Affinity purified IgY on human C4 agarose</span>
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            <span> </span>
            <span><p>Only one precipitin arc in immunodiffusion against normal human serum or human complement component C4. Only one precipitin arc in immunoelectrophoresis against normal human serum or human complement component C4.</p><p>ELISA has been performed on C4 deposition using human and mouse serum.</p></span>
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       <h3>Related products</h3>
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          <span>Related products</span>
          <span><p><span style="margin: 0pt; padding: 0pt;"><a href="https://www.agrisera.com/en/artiklar/animal-cell-biology/mammalian-proteins/immunology/complement-component-c4-human-labelled-with-biotin-.html" target="_blank">IMS06-032-304</a> | anti-Complement component C4, biotinylated<br /></span></p><p><span style="margin: 0pt; padding: 0pt;"><a href="https://www.agrisera.com/en/artiklar/animal-cell-biology/mammalian-proteins/immunology/complement-component-c4c-human.html" target="_blank">IMS01-031-305</a> | anti-Complement component C4c<br /></span></p><p><span style="margin: 0pt; padding: 0pt;"><a href="https://www.agrisera.com/en/artiklar/animal-cell-biology/mammalian-proteins/immunology/cfh-complement-factor-h.html" target="_blank">IMS01-066-309</a> | anti-Complement factor H<br /></span></p><p><a href="https://www.agrisera.com/en/artiklar/animal-cell-biology/secondary-antibodies-2/anti-hen-igy-secondary-antibodies/index.html" target="_blank">Secondary antibodies</a></p></span>
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       <h3>Background</h3>
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              <span>Background</span>
              <span><p><strong>Complement component C4</strong> consists of three polypeptide chains (alpha, molecular weight 95 kDa; beta, molecular weight 75 kDa and gamma, molecular weight 33 kDa) and is usually present in serum at 200-600 mg/L. It is a protein of the classical complement pathway. When activated by C1s, peptide C4a is released and the generated C4b binds C2 which is in turn cleaved by C1s to produce the classical pathway C3 convertase, namely C4b2a. C4b also has opsonin activity and binds to macrophages and neutrophils via their CR1 receptor.</p></span>
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<p><strong>Agrisera supports these plant societies <br /><a href="https://aspb.org/" target="_blank" rel="noopener" title="American Society of Plant Biology"><img src="https://www.agrisera.com/dokument/bibliotek/Image/aspb.png" width="41" height="40" alt="" /></a>    <a href="https://www.fespb.org/" target="_blank" rel="noopener" title="The Federation of European Society of Plant Biology"><img src="https://www.agrisera.com/dokument/bibliotek/Image/fesbp_logo_green_.png" width="39" height="40" alt="" /></a>    <a href="http://cspb-scbv.ca/" target="_blank" rel="noopener" title="Canadian Society of Plant Biologists"><img src="https://www.agrisera.com/dokument/bibliotek/Image/Canadian Society Logo 2 color_rotated_transparent_350.gif" width="40" height="40" alt="" /></a>    <a href="http://www.photosynthesisresearch.org/" target="_blank" rel="noopener" title="International Society of Photosynthesis Research"><img src="https://www.agrisera.com/dokument/bibliotek/Image/ispr_.png" width="47" height="50" alt="" /></a>    <a href="http://spps.se/" target="_blank" rel="noopener" title="Scandinavian Plant Physiology Society"><img src="https://www.agrisera.com/dokument/bibliotek/Image/SPPS_trans.png" width="52" height="37" alt="" /></a></strong><a style="padding: 4px 8px;" href="https://aspb.org/" title="American Society of Plant Biology" target="_blank" rel="noopener"></a></p>
<p><strong>The PSL Alliance</strong></p>
<p><a href="https://pivotalscientific.com/our-consultancy-services/the-psl-alliance" target="_blank" rel="noopener" title="The PSL Alliance"><img src="https://www.agrisera.com/dokument/bibliotek/Image/psl_.png" width="67" height="40" alt="" /></a></p>
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