F7 | Coagulation factor VII
IMS01-118-307 | Clonality: Polyclonal | Host: Hen | Reactivity: Human
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Purified full length recombinant protein UniProt:P08709
he IgY fraction is isolated by a two-step PEG precipitation procedure followed by ammonium sulphate precipitation
Factor VII is a 52 kDa multi-domain, single chain plasma glycoprotein synthesised in the liver and having abnormal circulating concentration of between 400 and 600 g/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, Factor Xa, Factor IXa or Factor XIIa. Factor VIIa converts Factor X to Factor Xa, which in turn converts prothrombin to thrombin.