FN | Fibronectin, Biotin conjugated
IMS06-060-315 | Clonality: Polyclonal | Host: Hen | Reactivity: Human
- Product Info
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Immunogen: Purified, full length native protein UniProt:P02751
Host: Chicken Clonality: Polyclonal Purity: Immunogen affinity purified IgY in 0.15M sodium chloride, 0.02M sodium phosphate, 0.1% sodium azide., pH 7.2. Format: Liquid Quantity: 100 µl (1 mg/ml) Storage: Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. Tested applications: Western blot (WB) Recommended dilution: 1 : 5 000 (WB) Expected | apparent MW: 263 kDa
- Reactivity
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Confirmed reactivity: Human Predicted reactivity: Bovine, Mouse Not reactive in: No confirmed exceptions from predicted reactivity are currently known - Additional Information
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Additional information: Affinity purified IgY on human fibronectin agarose Additional information (application): Before labelling: only one precipitin arc in immunodiffusion against normal human serum or human fibronectin, Only one precipitin arc in immunoelectrophoresis against normal human serum or human fibronectin, Specific in immunoblotting against human fibronectin - Background
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Background: Fibronectin is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. It occurs as dimer of two 200 kDa subunits. Fibronectin has binding domains for bacterial proteins, collagens, heparin-like molecules and fibrin. Cellular fibronectin is widely distributed in the stroma of malignant tumours.
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