IFNG | Interferon gamma
IMS01-145-319 | Clonality: Polyclonal | Host: Chicken | Reactivity: Human
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purified full length recombinant protein (Actimmune®, Genentech Inc.)
Interferon gamma (P01579) is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN.
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