IL2 | Interleukin-2

IMS01-127-320 | Clonality: Polyclonal | Host: Chicken | Reactivity: Human

Product Information

Immunogen

purified full length recombinant protein UniProt: P60568

Host Chicken

Clonality Polyclonal

Purity Total IgY fraction

Format Liquid in 0.9% NaCl, 0.1% sodium azide

Quantity 100 µl (9.2 mg/ml)

Storage Store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.

Tested applications Total, purified IgY

Recommended dilution 1 : 1000-1 : 5 000 (ELISA), 1 : 1000-1 : 5 000 (WB)

Expected | apparent MW

17kDa

Reactivity

Confirmed reactivity Human

Predicted reactivity Primates

Not reactive in No confirmed exceptions from predicted reactivity are currently known.

Application examples

Additional information

Additional information The IgY fraction is isolated by a two-step PEG precipitation. procedure followed by ammonium sulphate precipitation.

The antibody, in dilution 1: 1000, will detect 10 ng of interleukin-2 in immunoblotting.

Related products

IMS01-145-319 | Anti-Interferon gamma, chicken antibodies

Secondary antibodies

Background

Human interleukin-2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin-4 (IL4) and interleukin-7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies.