KLK5 | Kallikrein 5

Name: KLK5 | Kallikrein 5
SKU: AS06 102
Price: 394 EUR
Availability: InStock

AS06 102 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human

KLK5 | Kallikrein 5 in the group Antibodies Human Cell Biology / Other proteins at Agrisera AB (Antibodies for research) (AS06 102)

Product Information

Immunogen

KLH-conjugated mix of two synthetic peptides: one chosen from C-terminal and the other one from midregion of human KLK5 Q9Y337

Host Rabbit

Clonality Polyclonal

Purity Serum

Format Lyophilized

Quantity 200 µl

Reconstitution For reconstitution add 200 µl of sterile water

Storage Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Tested applications Western blot (WB)

Recommended dilution 1 : 1000 (WB)

Expected | apparent MW

32 | 37 kDa

Reactivity

Confirmed reactivity Human

Predicted reactivity Human

Not reactive in No confirmed exceptions from predicted reactivity are currently known

Application examples

Application example

Additional information

Antibody is recognizing denatured active Kallikrein 5

Background

Human Kallikrein 5 (KLK5) is a serine protease produced in its inactive form. It is found in catalytically active form in stratum corneum. It has been reported to degrade desmosomes/corneodesmosomes, suggesting that it is involved in desquamtion. Egelrud et al. (2005) hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. J Invest Dermatol, 124(1):198-203.Alternative names: stratum corneum tryptic enzyme, Kallikrein-like protein 2, KLK-L2

Product citations

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Confirmed reactivity:	Human
predicted reactivity:	Human
not reactive in:	No confirmed exceptions from predicted reactivity are currently known
additional information (application):	Antibody is recognizing denatured active Kallikrein 5
Picture (footer):	Application example
background:	Human Kallikrein 5 (KLK5) is a serine protease produced in its inactive form. It is found in catalytically active form in stratum corneum. It has been reported to degrade desmosomes/corneodesmosomes, suggesting that it is involved in desquamtion. Egelrud et al. (2005) hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. J Invest Dermatol, 124(1):198-203.Alternative names: stratum corneum tryptic enzyme, Kallikrein-like protein 2, KLK-L2
calculated \| apparent molecular mass [kDa]:	32 \| 37 kDa
Clonality:	Polyclonal
Format:	Lyophilized
Host:	Rabbit
immunogen:	KLH-conjugated mix of two synthetic peptides: one chosen from C-terminal and the other one from midregion of human KLK5 Q9Y337
Purity:	Serum
Quantity:	200 µl
recommended dilution:	1 : 1000 (WB)
Reconstitution:	For reconstitution add 200 µl of sterile water
storage:	Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
tested applications:	Western blot (WB)