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Super Deal

Primary/Secondary/ECL



Add only 20 € to your primary antibody purchase
and you will also receive:

- Secondary antibody
Goat anti-rabbit, HRP conjugated
(to be used >1: 25 000)

- Two chemiluminescent detection reagents
Agrisera ECL Bright/SuperBright,  for 10 midi blots (picogram and femtogram detection range)

AS18 PrimarySecondaryECL

MYST4 | histone acetyltransferase KAT6B

AS05 078  |  Clonality: Polyclonal  |  Host: Rabbit  |  Reactivity:Bovine

MYST4 | histone acetyltransferase KAT6B in the group Human/Animal Antibodies / Human Proteins / Other Human proteins at Agrisera AB (Antibodies for research) (AS05 078)

PRODUCT INFORMATION IN PDF

Qty: 
416 €

Datasheet Add review
product information
Background

MYST4 (KAT6B), EC=2.3.1.48, is a transcriptional coactivator with histone acetyltransferase activity. This protein is essential for normal mouse embryo development.  Mouse mutants for MYST4 show craniofacial abnormalities, retards in post-natal development, defaults in the nervous system and neurogenique problems.  Abnormal chromosomic rearengements of MYST4 with the CBP gene is involved in acute myeloid leukaemia (AML)-M4.  Furthermore, in the ovary and the testis of mammals, MYST4 is mainly localized in specialized cells involved in male and female gametogenesis. Alternative names: Histone acetyltransferase MOZ2, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4, Monocytic leukemia zinc finger protein-related factor.

Immunogen

KLH-conjugated synthetic peptide chosen from a bovine histone acetyltrasferase MYST4 A7E390
Host Rabbit
Clonality Polyclonal
Clone
Purity Affinity purified serum
Format Lyophilized in PBS pH 7.4
Quantity 100 ĩg
Reconstitution For reconstitution add 125 ĩl of sterile water.
Storage Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Tested applications Imunohistochemistry (IHC) Immunoprecipitation (IP), Western blot (WB)
Related products

Secondary antibodies
Additional information Antibody has been used on extracts from bovine brain, thymus, muscle, lung, heart, liver, kidney and spleen
application information
Recommended dilution 1 : 1000 (IHC), 1 :7500 (WB)
Expected | apparent MW

230 kDa
Confirmed reactivity bovine, antibody will also react with bovine MYST4 isoforms (MORF and MORF)
Predicted reactivity

Black flying fox, Human (isoform 2,3), Mouse (isoform 2,3,4), Vampire bat
Not reactive in Plants
Additional information Blocking used in IHC was done with 5% dry milk. Secondary antibodyused: Fluorescein-conjugated goat anti-rabbit IgG (Molecular Probes) diluted 1:1000.
Selected references McGraw et al. (2007). Investigation of MYST4 histone acetyltransferase and its involvement in mammalian gametogenesis. BMC Dev.Biol. 7:123.

||| For other applications, usage on species other than stated above or any other questions, please use the LiveChat option or contact us at support@agrisera.com