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p21 WAF-1 (clone WA-1)

AS16 4000 | Clonality: Monoclonal | Host: Mouse | Reactivity: Human

p21 WAF-1 (clone WA-1) in the group Antibodies for Human/Animal  / Human Proteins / Developmental biology at Agrisera AB (Antibodies for research) (AS16 4000)

DATA SHEET IN PDF

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329
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Product name, number (Agrisera, Sweden)

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Product Information

Immunogen Human p21 protein. UniProt: P38936
Host Mouse
Clonality Monoclonal
Subclass/isotype IgG1
Purity Protein A/G purified
Format Liquid
Quantity 100 µg
Storage Store at -20°C.
Tested applications ELISA (ELISA), Western blot (WB)
Recommended dilution 1-10 µg/ml (WB) The optimal working dilution should be determined by the investigator.

Reactivity

Confirmed reactivity Human
Not reactive in No confirmed exceptions from predicted reactivity are currently known.

Application examples

Additional information

Additional information Provided in phosphate buffered saline, contains 0.08% sodium azide.

Detects a 21 kDa protein in MCF7 cells. Can be used with either frozen or paraffin embedded tissue sections.

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Background

Background The expression of p21 is mostly induced by p53, usually in response to DNA damage induced by cytotoxic agents. p21 interrupts the cell cycle and prevents the replication of the cell containing genomic errors. p21 also inhibits Cdk2, Cdk3, Cdk4 and Cdk6 to stop the cell cycle.

Alternative names: Cyclin-dependent kinase inhibitor 1

Product citations

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