p53 (a,a, 16-25) (clone X77)
AS16 3999 | Clonality: Monoclonal | Host: Mouse | Reactivity: Human, Mouse, Xenopus

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Product Information
Immunogen
Full length Xenopus p53 protein. UniProt: P04637
Host
Mouse
Clonality
Monoclonal
Subclass/isotype
IgG1
Purity
Immunoglobulin IgG1, Protein A/G purified.
Format
Liquid
Quantity
100 ĩg
Storage
Store at -20°C.
Tested applications
ELISA (ELISA), Immunoprecipitation (IP), Western blot (WB)
Recommended dilution
1-10 ĩg/ml (WB) The optimal working dilution should be determined by the investigator
Reactivity
Confirmed reactivity
Human, Mouse, Xenopus
Not reactive in
No confirmed exceptions from predicted reactivity are currently known
Application examples
Additional information
Additional information
Provided in phosphate buffered saline, contains 0,08% sodium azide
Background
Background
p53 (a.a. 16-25) is a transcription factor that acts as a tumor suppressor which cause growth arrest or apoptosis depending on different circumstances or cell type. p53 also play an important role in cell cycle regulation as a trans-activator.
The most common alteration in human cancer is disruption of the p53 signalling pathway through various mechanisms.
The most common alteration in human cancer is disruption of the p53 signalling pathway through various mechanisms.
Product citations
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