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p53 (a,a, 16-25) (clone X77)

AS16 3999 | Clonality: Monoclonal | Host: Mouse | Reactivity: Human, Mouse, Xenopus

p53 (a,a, 16-25) (clone X77) in the group Antibodies Human Cell Biology / Cancer at Agrisera AB (Antibodies for research) (AS16 3999)



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Product Information

Immunogen Full length Xenopus p53 protein. UniProt: P04637
Host Mouse
Clonality Monoclonal
Subclass/isotype IgG1
Purity Immunoglobulin IgG1, Protein A/G purified.
Format Liquid
Quantity 100 ĩg
Storage Store at -20°C.
Tested applications ELISA (ELISA), Immunoprecipitation (IP), Western blot (WB)
Recommended dilution 1-10 ĩg/ml (WB) The optimal working dilution should be determined by the investigator

Reactivity

Confirmed reactivity Human, Mouse, Xenopus
Not reactive in No confirmed exceptions from predicted reactivity are currently known

Application examples

Additional information

Additional information Provided in phosphate buffered saline, contains 0,08% sodium azide

Related products

Background

Background p53 (a.a. 16-25) is a transcription factor that acts as a tumor suppressor which cause growth arrest or apoptosis depending on different circumstances or cell type. p53 also play an important role in cell cycle regulation as a trans-activator. 
The most common alteration in human cancer is disruption of the p53 signalling pathway through various mechanisms.

Product citations

immunogen: Full length Xenopus p53 protein. UniProt: P04637
Sub class: IgG1
Host: Mouse
Clonality: Monoclonal
Purity: Immunoglobulin IgG1, Protein A/G purified.
Format: Liquid
Quantity: 100 ĩg
storage: Store at -20°C.
tested applications: ELISA (ELISA), Immunoprecipitation (IP), Western blot (WB)
recommended dilution: 1-10 ĩg/ml (WB) The optimal working dilution should be determined by the investigator
Confirmed reactivity: Human, Mouse, Xenopus
not reactive in: No confirmed exceptions from predicted reactivity are currently known
additional information: Provided in phosphate buffered saline, contains 0,08% sodium azide
background: p53 (a.a. 16-25) is a transcription factor that acts as a tumor suppressor which cause growth arrest or apoptosis depending on different circumstances or cell type. p53 also play an important role in cell cycle regulation as a trans-activator. 
The most common alteration in human cancer is disruption of the p53 signalling pathway through various mechanisms.

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