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p53 (a.a. 16-25) (clone X77)

AS16 3999 | Clonality: Monoclonal | Host: Mouse | Reactivity: Human, Mouse, Xenopus

p53 (a.a. 16-25) (clone X77) in the group Antibodies for Human/Animal  / Human Proteins / Cancer at Agrisera AB (Antibodies for research) (AS16 3999)

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Product Information

Immunogen Full length Xenopus p53 protein. UniProt: P04637
Host Mouse
Clonality Monoclonal
Subclass/isotype IgG1
Purity Protein A/G purified
Format Liquid
Quantity 100 µg
Storage Store at -20°C.
Tested applications ELISA (ELISA), Immunoprecipitation (IP), Western blot (WB)
Recommended dilution 1-10 µg/ml (WB) The optimal working dilution should be determined by the investigator.

Reactivity

Confirmed reactivity Human, Mouse, Xenopus
Not reactive in No confirmed exceptions from predicted reactivity are currently known.

Application examples

Additional information

Additional information Provided in phosphate buffered saline, contains 0.08% sodium azide.

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Background

Background p53 (a.a. 16-25) is a transcription factor that acts as a tumor suppressor which cause growth arrest or apoptosis depending on different circumstances or cell type. p53 also play an important role in cell cycle regulation as a trans-activator. 
The most common alteration in human cancer is disruption of the p53 signalling pathway through various mechanisms.

Product citations

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