p53 (a,a, 371-380) (clone Pab122)

Name: p53 (a,a, 371-380) (clone Pab122)
Brand: IKP
SKU: AS16 4002
Price: 348 EUR
Availability: InStock

AS16 4002 | Clonality: Monoclonal | Host: Mouse | Reactivity: Human, Mouse, Rat, Monkey, Hamster

p53 (a,a, 371-380) (clone Pab122) in the group Antibodies Human Cell Biology / Cancer at Agrisera AB (Antibodies for research) (AS16 4002)

Product Information

Immunogen KLH-conjugated synthetic peptide derived from the rat alpha1E calcium channel. UniProt: Human, Q9BRQ8, Mouse, Q8BUE4

Host Mouse

Clonality Monoclonal

Subclass/isotype IgG2b

Purity Immunoglobulin IgG2b, Protein A/G purified.

Format Liquid

Quantity 100 µg

Storage Store at -20°C.

Tested applications Flow Cytometry (Flow cyt), Immunofluorescense (IF), Immunoprecipitation (IP)

Recommended dilution 5-10 µg/ml (WB) The optimal working dilution should be determined by the investigator

Reactivity

Confirmed reactivity Human, Mouse, Rat, Monkey, Hamster

Not reactive in No confirmed exceptions from predicted reactivity are currently known

Application examples

Additional information

Additional information Provided in phosphate buffered saline, contains 0,08% sodium azide

Background

p53 is a transcription factor that acts as a tumor suppressor which cause growth arrest or apoptosis depending on different circumstances or cell type. p53 also play an important role in cell cycle regulation as a trans-activator.
The most common alteration in human cancer is disruption of the p53 signalling pathway through various mechanisms.

Product citations

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immunogen:	KLH-conjugated synthetic peptide derived from the rat alpha1E calcium channel. UniProt: Human, Q9BRQ8, Mouse, Q8BUE4
Sub class:	IgG2b
Host:	Mouse
Clonality:	Monoclonal
Purity:	Immunoglobulin IgG2b, Protein A/G purified.
Format:	Liquid
Quantity:	100 µg
storage:	Store at -20°C.
tested applications:	Flow Cytometry (Flow cyt), Immunofluorescense (IF), Immunoprecipitation (IP)
recommended dilution:	5-10 µg/ml (WB) The optimal working dilution should be determined by the investigator
Confirmed reactivity:	Human, Mouse, Rat, Monkey, Hamster
not reactive in:	No confirmed exceptions from predicted reactivity are currently known
additional information:	Provided in phosphate buffered saline, contains 0,08% sodium azide
background:	p53 is a transcription factor that acts as a tumor suppressor which cause growth arrest or apoptosis depending on different circumstances or cell type. p53 also play an important role in cell cycle regulation as a trans-activator. The most common alteration in human cancer is disruption of the p53 signalling pathway through various mechanisms.