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p53 (a.a. 371-380) (clone Pab122)

AS16 4002 | Clonality: Monoclonal | Host: Mouse | Reactivity: Human, Mouse, Rat, Monkey, Hamster

p53 (a.a. 371-380) (clone Pab122) in the group Antibodies for Human/Animal  / Human Proteins / Cancer at Agrisera AB (Antibodies for research) (AS16 4002)

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Product Information

Immunogen KLH-conjugated synthetic peptide derived from the rat alpha1E calcium channel. UniProt: Human, Q9BRQ8, Mouse, Q8BUE4
Host Mouse
Clonality Monoclonal
Subclass/isotype IgG2b
Purity Protein A/G purified
Format Liquid
Quantity 100 µg
Storage Store at -20°C.
Tested applications Flow Cytometry (Flow cyt), Immunofluorescense (IF), Immunoprecipitation (IP)
Recommended dilution 5-10 µg/ml (WB) The optimal working dilution should be determined by the investigator.

Reactivity

Confirmed reactivity Human, Mouse, Rat, Monkey, Hamster
Not reactive in No confirmed exceptions from predicted reactivity are currently known.

Application examples

Additional information

Additional information Provided in phosphate buffered saline, contains 0.08% sodium azide.

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Background

Background

p53 is a transcription factor that acts as a tumor suppressor which cause growth arrest or apoptosis depending on different circumstances or cell type. p53 also play an important role in cell cycle regulation as a trans-activator. 
The most common alteration in human cancer is disruption of the p53 signalling pathway through various mechanisms.

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