IMS01-133-332 | Clonality: Polyclonal | Host: Hen | Reactivity: Pseudomonas aeruginosa
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whole, formaldehyde killed, bacteria, strains PAO1 and Habs1
The main reactivity of this antibody is flagellin a and b in Pseudomonas, which will lead to variation in positions of detected bands in western blot technique. Nilsson et al. (2007).
Antibodies have been tested against E.coli, Klebsiella and Streptococcus aureus and no significant cross-reactivity has been detected.
Pseudomonas aeruginosa is Gram-negative, aerobic, rod-shaped bacteria with unipolar motility. An opportunistic human pathogen, P. aeruginosa is also an opportunistic pathogen of plants. P. aeruginosa bacterias are clinically important because they are resistant to most antibiotics and they are capable of surviving in conditions that few other organisms can tolerate. Pseudomonas is often encountered in hospital and clinical work because it is a major cause of hospital acquired (nosocomal) infections. Its main targets are immunocompromised individuals, burn victims, and individuals on respirators or with precipitation procedure followed by indwelling catheters. Additionally, these pathogens colonize the lungs of cystic fibrosis patients. P. aeruginosa is often identified by its pearlescent appearance and grape-like odor in vitro. Definitive clinical identification of P. aeruginosa includes identifying the production of both pyocyanin and fluorescein as well as its ability to grow at 42°C.
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