A1AGP | Alpha-1-acid glycoprotein

AS01 015 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Rat

Product Information

Immunogen

rat alpha-1-acid glycoprotein (A1AGP) or orosomucoid (OMD) UniProt: P02764

Host Rabbit

Clonality Polyclonal

Purity Serum

Format Lyophilized

Quantity 200 µl

Reconstitution For reconstitution add 200 µl of sterile water

Storage Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Tested applications ELISA (ELISA), Immunoprecipitation (IP), Radioimmunoassay (RIA), Western blot (WB)

Recommended dilution 1 : 2000 (WB); use at an assay dependent dilution in (ELISA), (IP), (RIA)

Expected | apparent MW

44 kDa

Reactivity

Confirmed reactivity Rat

Predicted reactivity Rat

Not reactive in No confirmed exceptions from predicted reactivity are currently known

Application examples

Additional information

Background

Alpha-1-acid glycoprotein (A1AGP) or Orosomucoid (OMD) is a plasma glycoprotein synthesized by the liver. The protein is believed to regulate the interaction between blood cells and endothelial cells, and therefore also regulates the extravasation of the cells during infection and inflammation. A1AGP is a major acute phase reactant, both in man and in rat. It's concentration in blood plasma is elevated during acute inflammation, such as rheumatoid arthritis, bacterial infections, etc, and can be used for the diagnosis of inflammatory conditions.

Product citations

Selected references Olofsson et al. (2003) Identification and isolaton of dominant sesceptibility loci for pristane-induced arthritis. J Immunol, 171, 407-16.
Olofsson et al. (2002) Positional identification of Ncf1 as a gene that regulates arthritis severity in rats. Nat Genet, 33, 25-32.

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Confirmed reactivity:	Rat
predicted reactivity:	Rat
not reactive in:	No confirmed exceptions from predicted reactivity are currently known
calculated \| apparent molecular mass [kDa]:	44 kDa
Clonality:	Polyclonal
Format:	Lyophilized
Host:	Rabbit
immunogen:	rat alpha-1-acid glycoprotein (A1AGP) or orosomucoid (OMD) UniProt: P02764
Purity:	Serum
Quantity:	200 µl
recommended dilution:	1 : 2000 (WB); use at an assay dependent dilution in (ELISA), (IP), (RIA)
Reconstitution:	For reconstitution add 200 µl of sterile water
storage:	Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
tested applications:	ELISA (ELISA), Immunoprecipitation (IP), Radioimmunoassay (RIA), Western blot (WB)
background:	Alpha-1-acid glycoprotein (A1AGP) or Orosomucoid (OMD) is a plasma glycoprotein synthesized by the liver. The protein is believed to regulate the interaction between blood cells and endothelial cells, and therefore also regulates the extravasation of the cells during infection and inflammation. A1AGP is a major acute phase reactant, both in man and in rat. It's concentration in blood plasma is elevated during acute inflammation, such as rheumatoid arthritis, bacterial infections, etc, and can be used for the diagnosis of inflammatory conditions.
All references:	Olofsson et al. (2003) Identification and isolaton of dominant sesceptibility loci for pristane-induced arthritis. J Immunol, 171, 407-16. Olofsson et al. (2002) Positional identification of Ncf1 as a gene that regulates arthritis severity in rats. Nat Genet, 33, 25-32.