RTA | Ricin toxic A chain

AS17 4143 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Ricinus communis

Product Information

Immunogen Ricin A chain isolated from Ricinus communis var. Impala

Host Rabbit

Clonality Polyclonal

Purity Serum

Format Lyophilized

Quantity 50 µl

Reconstitution For reconstitution add 50 µl of sterile water

Storage Lyophilized antibody can be stored at -20°C for up to 3 years. Re-constituted antibody can be stored at 4°C for several days to weeks. Once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Tested applications ELISA (ELISA)

Recommended dilution

1: 10 000 (ELISA)

Reactivity

Confirmed reactivity Ricinus communis

Not reactive in No confirmed exceptions from predicted reactivity are currently known

Application examples

Additional information

Antibody is recognizing active toxin complex containing both, ricin A and B subunits

Related products

Related products AS17 4144 | Anti-RTB | Ricin toxic B chain rabbit antibodies
AS09 648 | Anti-Ricin (RTA subunit), clone MMA, mouse monoclonal antibody
AS09 649 | Anti-Ricin (whole molecule), clone MMH, mouse monoclonal antibody

Background

Background Ricin is a naturally occuring protein found in castor bean (Ricinus communis) acting as protein synthesis inhibitor. It is a toxin involved in plant defence. A chain of ricin can inactivate few thousands of ribosomes per minute. B chain facilitates the entry of A chain into the cell. Both protein chains, A and B must be present in order to produce an active toxin.

Ricin toxic A chain is an N-glycosylated heterodimer of approximately 60 to 65 kDa.