STX | saxitoxin, Total IgG (0.5 mg)

AS11 1647 | Clonality: Polyclonal | Host: Rabbit | Reactivity: saxitoxin


product information
Background		Saxitoxin (STX) is a neurotoxin that acts as a selective sodium channel blocker and is naturally produced by certain species of marine dinoflagellates (Alexandrium sp., Gymnodinium sp., Pyrodinium sp.) and cyanobacteria (Anabaena sp., some Aphanizomenon spp., Cylindrospermopsis sp., Lyngbya sp., Planktothrix sp.). Ingestion of STX (usually through shellfish contaminated by toxic algal blooms) is responsible for the human illness known as paralytic shellfish poisoning (PSP). Saxitoxin, one of the most potent natural toxins known, acts on the voltage-gated sodium channels of nerve cells, preventing normal cellular function and leading to paralysis.
Immunogen		BSA-conjugated saxitoxin
Host		Rabbit
Clonality		Polyclonal
Clone
Purity		total IgG
Format		Lyophilized
Quantity		0.5 mg
Reconstitution
Storage		Store at 4°C following reconstitution.
Tested applications		ELISA (ELISA)
Related products		AS11 1663 \| anti-saxitoxin, antibodies in serum format, small pack size - 0.1 ml AS11 1696 \| anti-saxitoxin, antibodies in serum format, larger pack size - 1 ml Secondary antibodies
Additional information		Antibodies are in a format of total IgG purified on protein A. Purified antibodies were dialized against dionized water.

application information
Recommended dilution		The optimal working dilution should be determined by the investigator.
Expected \| apparent MW		n.a.
Confirmed reactivity		Toxin from marine dinoflagellates, cyanobacteria and mussels
Predicted reactivity
Not reactive in		No confirmed exceptions from predicted reactivity are currently known.
Additional information		The term saxitoxin can also refer to the entire suite of related neurotoxins produced by these microorganisms, which include pure STX, neosaxitoxin (neoSTX), the gonyautoxins (GTX) and decarbamoylsaxitoxin (dcSTX).
Selected references		to be added when available

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