STX | saxitoxin, Total IgG (2.5 mg)
AS11 1690 | Clonality: Polyclonal | Host: Rabbit | Reactivity: saxitoxin
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Product Information
Immunogen
BSA-conjugated saxitoxin
Host
Rabbit
Clonality
Polyclonal
Purity
total IgG
Format
Lyophilized
Quantity
2.5 mg
Reconstitution
For reconstitution add 1.1 ml of sterile water.
Storage
Store at 4°C following reconstitution.
Tested applications
ELISA (ELISA)
Recommended dilution
The optimal working dilution should be determined by the investigator.
Reactivity
Confirmed reactivity
Toxin from marine dinoflagellates, cyanobacteria and mussels.
Not reactive in
No confirmed exceptions from predicted reactivity are currently known.
Application examples
Additional information
Additional information
Antibodies are provided as total IgG purified on protein A. Purified antibodies were dialized against dionized water.
The term saxitoxin can also refer to the entire suite of related neurotoxins produced by these microorganisms, which include pure STX, neosaxitoxin (neoSTX), the gonyautoxins (GTX) and decarbamoylsaxitoxin (dcSTX).
Background
Background
Saxitoxin (STX) is a neurotoxin that acts as a selective sodium channel blocker and is naturally produced by certain species of marine dinoflagellates (Alexandrium sp., Gymnodinium sp., Pyrodinium sp.) and cyanobacteria (Anabaena sp., some Aphanizomenon spp., Cylindrospermopsis sp., Lyngbya sp., Planktothrix sp.). Ingestion of STX (usually through shellfish contaminated by toxic algal blooms) is responsible for the human illness known as paralytic shellfish poisoning (PSP). Saxitoxin, one of the most potent natural toxins known, acts on the voltage-gated sodium channels of nerve cells, preventing normal cellular function and leading to paralysis.
Product citations
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