TH | Tyrosine Hydroxylase
AS13 2696 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Rat, Mouse and Guinea pig
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A synthetic peptide as part of human Tyrosine Hydroxylase conjugated to KLH. The peptide is homologous with the corresponding sequence derived from TH protein in rat.
After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
Immunohistochemical staining of catecholaminergic neurons in the rat brain stem.
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. It plays an important role in the physiology of adrenergic neurons.