TH | Tyrosine Hydroxylase

AS13 2696 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Rat, Mouse and Guinea pig

Product Information

Immunogen A synthetic peptide as part of human Tyrosine Hydroxylase conjugated to KLH, The peptide is homologous with the corresponding sequence derived from TH protein in rat,

Host Rabbit

Clonality Polyclonal

Purity Serum

Format Lyophilized

Quantity 100 µl

Reconstitution For reconstitution add 100 µl of sterile water

Storage After reconstitution keep aliquots at -20ºC for a higher stability. and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Tested applications Immunohistochemistry (IHC)

Recommended dilution 1 : 2000-1 : 5000, This is a superb antibody for detection of tyrosine hydroxylase containing neurons exhibiting an intense labelling with a negligible background, This antiserum has proven extremely useful for staining of catecholaminergic neurons, It stains nicely and intensely dendritic processes and fine nerve terminals, We recommend mouse or rat brain containing catecholaminergic neurons as a positive control for this antibody, for example brain stem or striatum, Optimal dilutions/concentrations should be determined by the end user

Reactivity

Confirmed reactivity Rat, Mouse and guinea pig

Application examples

Application examples Application example

Immunohistochemical staining of catecholaminergic neurons in the rat brain stem.

Additional information

Background

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. It plays an important role in the physiology of adrenergic neurons.

Product citations

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