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THDOC | Tetrahydrodeoxycorticosterone

AS06 192  |  Clonality: Polyclonal  |  Host: Hen  |  Reactivity: THDOC

THDOC | Tetrahydrodeoxycorticosterone in the group Antibodies Human Research / Neuroscience / Neurobiology at Agrisera AB (Antibodies for research) (AS06 192)



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Product Information

Immunogen

BSA-coupled THDOC

Host Chicken
Clonality Polyclonal
Purity Purified, total IgY (chicken egg yolk immunoglobulin) in PBS pH 8. Contains 0.02 % sodium azide.
Format Liquid
Quantity 100 ĩl
Storage Store at 4°C or at -20°C for long-term storage; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Tested applications Radioimmunoassay (RIA)
Recommended dilution 1 : 1000 (RIA)

Reactivity

Confirmed reactivity THDOC
Not reactive in No confirmed exceptions from predicted reactivity are currently known

Application examples

Additional information

Related products

Background

Background

TetraHydroDesOxyCorticosterone (THDOC) is a stress related neuroactive steroid. THDOC is a metabolite of desoxycoritcosterone (DOC) and progesterone and DOC is a steroid in the synthesis pathway to aldosterone. THDOC is produced by the adrenal in parallel with cortisol at stress and is regulated by  ACTH. THDOC is a potent positive modulator of the GABA A receptor. THDOC passes the blood-brain barrier and can be found in the brain after stress in nanomolar concentrations.

Product citations

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