THP | Allopregnanolone
AS04 041 | Clonality: Polyclonal | Host: Hen | Reactivity: Allopregnanolone
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100 µl will be enough to perform 60 double samples, generating standard curve and blank
Waters column Symmetry C18 3.5um 4.6 x 75mm with 3.9 x 20mm as guard column has been used
Allopregnanolone, (3alpha-hydroxy-5alpha-pregnan-20-ol), also known as 3alpha,5alpha-tetrahydroprogesterone or THP, is a neuroactive steroid secreted by the mammalian ovary and adrenal. It exerts its anesthetic, anxiolytic, and sedative/hypnotic effects through potentiation of GABA A receptors and its release is stimulated by trophic hormones in relation to stress and reproductive hormone secretion.