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TF | Transferrin

IMS02-020-322  |  Clonality: Polyclonal  |  Host: Hen  |  Reactivity: Human

TF | Transferrin  in the group Antibodies for Human/Animal  / Human Proteins / Immunology at Agrisera AB (Antibodies for research) (IMS02-020-322)

DATA SHEET IN PDF

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336
How to cite this product:
Product name, number (Agrisera, Sweden)

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Product Information

Immunogen

purified full length native protein UniProt: P02787

Host Chicken
Clonality Polyclonal
Purity Affinity purified IgY
Format Liquid in 0.15M sodium chloride, 0.02M sodium phosphate, 0.1% sodium azide, pH 7.2
Quantity 100 µl (1 µg/µl)
Storage Store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Tested applications Affinity purified IgY
Recommended dilution 1 : 1000 (WB)
Expected | apparent MW

77 kDa

Reactivity

Confirmed reactivity Human
Predicted reactivity Primates
Not reactive in No confirmed exceptions from predicted reactivity are currently known.

Application examples

Additional information

Additional information Affinity purified IgY on human tranferrin agarose
Only one precipitin arc in immunodiffusion against normal human serum, dilution 1: 10, or human transferrin. Only one precipitin arc in immunoelectrophoresis against normal human serum, or human transferrin.

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Secondary antibodies

Background

Background

Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains, each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.

Product citations

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