VEGF | Vascular endothelial growth factor
AS10 1575 | Clonality: Polyclonal | Host: Chicken | Reactivity:Human
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Immunogen KLH-conjugated synthetic peptide: APMAEGGGQNHHEVVKF, corresponding to aa 27-43 of human VEGF. Accesion number P15692.
Purity Total IgY
Format Liquid in 0.9% NaCl, 0.02% sodium azide
Quantity 0.2 mg
Storage Store at 4 to 8°C.
Tested applications Direct ELISA (ELISA), Immunohistochemistry (IHC)
Recommended dilution 1 : 2700 (ELISA), 1 : 1000 (IHC)
Expected | apparent MW
Confirmed reactivity Human
Predicted reactivity Baboon, Bovine, Macaque
Not reactive in No confirmed exceptions from predicted reactivity are currently known.
ELISA has been done with peptide used to elicit this antibody. IHC has been done on paraffin embedded sections.
Background VEGF | Vascular endothelial growth factor is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. When VEGF is overexpressed, it can contribute to disease. Cancers that can express VEGF are able to grow and metastasize. VEGF is sometimes referred to as vascular permeability factor.
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