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VRL-1 | Vanilloid receptor-like protein 1

AS13 2690 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Rat and Human

VRL-1 | Vanilloid receptor-like protein 1 in the group Antibodies Human Cell Biology / Neuroscience / Neurodegenerative diseases / Alzheimer's disease at Agrisera AB (Antibodies for research) (AS13 2690)



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Product Information

Immunogen KLH-conjugated, synthetic peptide (C-KNSASEEDHLPLQVLQSP) of rat VRL-1 protein (aa: 744-761)
Host Rabbit
Clonality Polyclonal
Purity Serum
Format Lyophilized
Quantity 100 ĩl
Reconstitution For reconstitution add 100 µl of sterile water
Storage After reconstitution keep aliquots at -20šC for a higher stability. and at 4šC with an appropriate antibacterial agent
Tested applications Immunohistochemistry (IHC), Immunofluorescence (IF), Western blot (WB)
Recommended dilution Recommended to be used at 1 : 1000-1 : 2000 and Western blot, for Immunofluorescence (frozen sections) at 1 : 50-1 : 200 in free-floating sections or paraffin embedded sections, Optimal dilutions/concentrations should be determined by the end user

Reactivity

Confirmed reactivity Rat, Human

Application examples

Application examples Application example



Immunofluorescence staining of human brain (midfrontal cortex, Alzheimer case) fixed in Zamboni. Dilution used: 1:50 (AS13 2690), free-floating sections, 40X magnification.



Additional information

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Background

Background

VRL-1 is ubiquitously expressed. Expressed in dorsal root ganglia, trigeminal ganglia, spinal chord (Lissauer's tract, dorsal horn and dorsal columns) (at protein level). PTM: N-glycosylated. PTM: Phosphorylated by PKA. It belongs to the transient receptor family. TrpV subfamily. It contains 3 ANK repeats.

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