VRL-1 | Vanilloid receptor-like protein 1

AS13 2690 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Rat and Human

Product Information

Immunogen KLH-conjugated, synthetic peptide (C-KNSASEEDHLPLQVLQSP) of rat VRL-1 protein (aa: 744-761)

Host Rabbit

Clonality Polyclonal

Purity Serum

Format Lyophilized

Quantity 100 µl

Reconstitution For reconstitution add 100 µl of sterile water

Storage After reconstitution keep aliquots at -20ºC for a higher stability. and at 4ºC with an appropriate antibacterial agent

Tested applications Immunohistochemistry (IHC), Immunofluorescence (IF), Western blot (WB)

Recommended dilution Recommended to be used at 1 : 1000-1 : 2000 and Western blot, for Immunofluorescence (frozen sections) at 1 : 50-1 : 200 in free-floating sections or paraffin embedded sections, Optimal dilutions/concentrations should be determined by the end user

Reactivity

Confirmed reactivity Rat, Human

Application examples

Application examples Application example

Immunofluorescence staining of human brain (midfrontal cortex, Alzheimer case) fixed in Zamboni. Dilution used: 1:50 (AS13 2690), free-floating sections, 40X magnification.

Additional information

Background

VRL-1 is ubiquitously expressed. Expressed in dorsal root ganglia, trigeminal ganglia, spinal chord (Lissauer's tract, dorsal horn and dorsal columns) (at protein level). PTM: N-glycosylated. PTM: Phosphorylated by PKA. It belongs to the transient receptor family. TrpV subfamily. It contains 3 ANK repeats.

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