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VRL-1

AS13 2690 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Rat and Human

VRL-1  in the group Antibodies for Human/Animal  / Human Proteins / Amyloid disorders / Alzheimer's disease at Agrisera AB (Antibodies for research) (AS13 2690)

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Product Information

Immunogen

A synthetic peptide of rat VRL-1 protein, conjugated to KLH.

Host Rabbit
Clonality Polyclonal
Purity Serum
Format Lyophilized
Quantity 100 µl
Reconstitution For reconstitution add 100 µl of sterile water.
Storage

After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent.

Tested applications Immunohistochemistry (IHC), Immunofluorescence (IF), Western blot (WB)
Recommended dilution Recommended to be used at 1 : 1000-1 : 2000 and Western blot, for Immunofluorescence at 1 : 50-1 : 200 in free-floating sections or paraffin embedded sections. Optimal dilutions/concentrations should be determined by the end user.

Reactivity

Confirmed reactivity Rat, Human

Application examples

Application examples Application example



Immunofluorescence staining of human brain (midfrontal cortex, Alzheimer case) fixed in Zamboni. Dilution used: 1:50 (AS13 2690), free-floating sections, 40X magnification.





Additional information

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Background

Background

VRL-1 is ubiquitously expressed. Expressed in dorsal root ganglia, trigeminal ganglia, spinal chord (Lissauer's tract, dorsal horn and dorsal columns) (at protein level). PTM: N-glycosylated. PTM: Phosphorylated by PKA. It belongs to the transient receptor family. TrpV subfamily. It contains 3 ANK repeats.

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