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product information
|
| background |
|
Factor VIIa (FVIIa) is a key serine protease involved in the initiation of the coagulation cascade. FVIIa requires tissue factor (TF), a membrane bound protein, as an essential cofactor for maximal activity towards its biological substrates Factor X, Factor IX and Factor VII (FVII). |
| immunogen |
|
recombinant human Factor VIIa (NovoSeven ®, Novo Nordisk A/S Denmark) |
| antibody format |
|
rabbit; |
polyclonal; |
|
affinity purified total IgG in PBS pH 7.4; |
lyophilized |
|
| quantity |
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500 ug |
- for reconstitution add 500 µl of sterile water |
|
| storage |
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store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them, to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes. |
| tested applications |
|
prothrombin assay with human plasma (PT), thrombin generation assay, inhibition assay with Factor VIIa with TF and a chromogenic substrate, indirect ELISA (I-ELISA) |
| related products |
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AS00 001 | anti-Coagulation factor VIIa (250 ug)
IMS01-118-307 | anti-Coagulation factor VII IMS01-015-308 | anti-Coagulation factor VIII
AS05 058 | anti-Coagulation factor IX IMS01-137-306 | anti-Coagulation factor XII
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| additional information |
|
no significant difference in binding to Factor VII and Factor VIIa |
||| For applications or usage on species others than stated above Agrisera offers a payment-after-testing option. To learn more about this or for any questions on this product, please use the LiveChat option in the left menu bar or contact us at support@agrisera.com
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