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hScrib | Protein LAP4

345 €

AS06 155  |  clonality: polyclonal  |  host: rabbit  |  reactivity: human

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Item No:
AS06 155

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Background

Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK.  The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4

Immunogen

GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains

Host Rabbit
Clonality Polyclonal
Clone
Purity Serum
Format Lyophilized
Quantity 100 ĩl
Reconstitution For reconstitution add 100 ĩl of sterile water
Storage

store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Tested applications Western blot (WB)
Related products

Secondary antibodies

Additional information
application information
Recommended dilution

1: 5 000 with standard ECL (WB)

Expected | apparent MW

175 kDa

Confirmed reactivity

human

Predicted reactivity

human

Not reactive in

no confirmed exceptions from predicted reactivity known in the moment

Additional information

reactivity showed on dilluted human cell culture extracts

Selected references

to be added when available



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