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ASyM-biotinylated | Mouse anti-human alpha synuclein N-terminal

540 €

AS13 2719B  | clonality: monoclonal  |  host: mouse  |  reactivity: human

 

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AS13 2719B

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product information
Background

Alpha-synuclein is normally an unstructured soluble protein that can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy-bodies, and multiple system atrophy. In analogy to many other amyloid associated disorders, alpha-synuclein may also form oligomeric assemblies. These small and soluble forms have been suggested to exert a stronger tissue damaging effect as compared to the monomeric and fibrillar counterpart. Using a recently developed technique a monoclonal oligomer-specific antibody has been designed.  

Immunogen

synthetic peptide derived from human alpha-synuclein N-terminal Met1-Val15

Host Mouse
Clonality Monoclonal
Clone IgG2a
Purity Affinity purified
Format Lyophilized
Quantity 50 ĩg
Reconstitution For reconstitution add 50 ĩl of sterile water.
Storage

For short time storage add sodium azide and store at +4°C.
For long time storage store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Tested applications ELISA (ELISA)
Related products

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AS13 2718B | anti-ASyO5-biotinylated |  Mouse anti-human alpha-synuclein | oligomer-specific, monoclonal antibodies

AS08 358 | anti-SNCA | Alpha-synuclein, rabbit antibodies

Secondary antibodies

protein extraction buffer

Secondary antibodies

Additional information

This antibody is biotinylated.

Cross reactivity of this antibody to synuclein beta was not determined.

application information
Recommended dilution

2-4 ug/ml (ELISA capture)

Expected | apparent MW

14 kDa

Confirmed reactivity

human

Predicted reactivity n.a.
Not reactive in

no confirmed exceptions from predicted reactivity are currently known

Additional information

to be added when available

Selected references

to be added when available, antibody released in April 2014



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