AS15 2887-HRP | Clonality: Monoclonal | Host: Mouse | Reactivity: 8-OHdG
|Data sheet||Protocols||Add review|
|Purity:||Antigen affinity purified, HPR conjugated|
|recommended dilution:||1 : 1000 (ELISA)|
|storage:||Store at 4°C. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.|
|tested applications:||ELISA (ELISA)|
|background:||8-hydroxy-2-deoxy Guanosine (8-OHdG) is produced by the oxidative damage of DNA by reactive oxygen and nitrogen species and serves as an established marker of oxidative stress. 1-4 Hydroxylation of guanosine occurs in response to both normal metabolic processes and a variety of environmental factors (i.e., anything that increases reactive oxygen and nitrogen species). Increased levels of 8-OHdG are associated with the aging process as well as with a number of pathological conditions including cancer, diabetes, and hypertension.|
|Confirmed reactivity:||8-OHdG in cell culture, plasma, urine or other samples|
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