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APP | Amyloid Precursor Protein (C-term)

AS20 4456 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human, mouse, rat

APP | Amyloid Precursor Protein (C-term) in the group Antibodies for Human/Animal  / Human Proteins / Amyloid disorders / Alzheimer's disease at Agrisera AB (Antibodies for research) (AS20 4456)

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Product Information

Immunogen

Synthetic peptide amino acids: 737-751 of human APP UniProt: P05067 or 85-99 of the C99 generated by secretases. 

Host Rabbit
Clonality Polyclonal
Purity Affinity purified on antigen
Format  Liquid in PBS containing 0.02% sodium azide as a preservative.
Quantity 100 µg
Storage Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tubes.
Tested applications Western blot (WB)
Recommended dilution 0.5 - 1 µg/ml (WB)
Expected | apparent MW 86.9 | 120 kDa

Reactivity

Confirmed reactivity Human, mouse, rat
Predicted reactivity Chicken, monkey and other species, please inquire
Not reactive in No confirmed exceptions from predicted reactivity are currently known.

Application examples

Additional information

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Background

Background

APP is an integral membrane protein found in any tissues and concentrated in the synapses of neurons. It is known as the precursor molecule generating amyloid beta (Aβ), and the amyloid fibrillar form is the primary component of amyloid plaques found in the brains of patients with Alzheimer's disease.

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