APP | Amyloid Precursor Protein (C-term)
AS20 4456 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Human, mouse, rat
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Product Information
Immunogen
Synthetic peptide amino acids: 737-751 of human APP UniProt: P05067 or 85-99 of the C99 generated by secretases.
Host
Rabbit
Clonality
Polyclonal
Purity
Affinity purified on antigen
Format
Liquid in PBS containing 0.02% sodium azide as a preservative.
Quantity
100 µg
Storage
Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tubes.
Tested applications
Western blot (WB)
Recommended dilution
0.5 - 1 µg/ml (WB)
Expected | apparent MW
86.9 | 120 kDa
Reactivity
Confirmed reactivity
Human, mouse, rat
Predicted reactivity
Chicken, monkey and other species, please inquire.
Not reactive in
No confirmed exceptions from predicted reactivity are currently known.
Application examples
Additional information
Background
Background
APP is an integral membrane protein found in any tissues and concentrated in the synapses of neurons. It is known as the precursor molecule generating amyloid beta (Aβ), and the amyloid fibrillar form is the primary component of amyloid plaques found in the brains of patients with Alzheimer's disease.
Product citations
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