BoNT-A | Botulinum toxin A
AS16 4086 | Clonality: Polyclonal | Host: Rabbit | Reactivity: Botulinum toxin A

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Product Information
Immunogen
Recombinat C-terminal heavy chain of BoNT/A1, residues 876–1296, which was cloned into a pET28a His-tag vector (Novagen) and overexpressed in E.coli. UniProt: https://www.uniprot.org/uniprot/P10845
Host
Rabbit
Clonality
Polyclonal
Purity
Total IgG. Protein G purified in PBS pH 7.4.
Format
Lyophilized
Quantity
0,5 mg
Reconstitution
For reconstitution add 250 ĩl, of sterile water
Storage
Lyophilized antibody can be stored at -20°C for up to 3 years. Re-constituted antibody can be stored at 4°C for several days to weeks. Once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Tested applications
ELISA (ELISA)
Recommended dilution
To be determined by end user
Reactivity
Confirmed reactivity
Botulinum toxin A heavy chain
Not reactive in
No confirmed exceptions from predicted reactivity are currently known
Application examples
Additional information
Background
Background
Botulinum toxin is a toxin produced by the anaerobic, gram-positive, bacterium of the genus Clostridium (C. botulinum, C. butyricum, C. baratii and C. argentinense). These strains are widely distributed and can be found in soil and dust. Eight types of botulinum toxin are distinguished, named type A–H. Type A and B are capable of causing disease in humans (botulism) and have longest activity in vivo, and are also used commercially (BOTOX) and medically. Types C–G are less common; types E and F can cause disease in humans, while the other types cause disease in other animals. BotA is cleaved into two chains: heavy and light.
Alternative name: Bontoxilysin-A
Alternative name: Bontoxilysin-A
Product citations
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