HDEL | Endoplasmic reticulum retention signal (clone 2E7)
AS10 683 | Clonality: monoclonal | Host: Mouse | Reactivity:Barnyard Grass (E. crus-galli), B. vulgaris, G. hirsutum, H. vulgare, Sorghum sp., V. radiata, S. cerevisiae, D. melanogaster

Data sheet | Product citations | Protocols | Add review |
Product Information
Synthetic HDEL peptide corresponding to the C-terminus of yeast Bip protein
78 kDa
Reactivity
Application examples
Additional information
Antibody in concentration 1 µg/ml was sufficient for detection of HDEL-containing proteins in 10 µg of yeast cell lysate by colorimetric western blot. Clone 2E7.
For western blot results, immunofluorescence and immunogold images please referr to Napier et al. 1992.
Background
HDEL (his-asp-glu-leu) is a C-terminal tertapeptide found in yeast and plants which allows sorting of resident soluble proteins in the lumen of the endoplasmic reticulum.
Product citations
Napier et al. (1992). Immunological evidence that plants use both HDEL and KDEL for targeting proteins to the endoplasmic reticulum. J Cell Sci. 102: 261-271.
Related products: HDEL | Endoplasmic reticulum retention signal (clone 2E7)
Now available only...